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Discovering how to create appropriate cell-matrix interactions for improving tendon repair
Figure 1a. Average load-displacement failure curve
The murine patellar tendon healing tissue showed significantly decreased structural properties at 2-, 5-, and 8-weeks compared to normal PT (p < 0.05). There were no significant differences in structural biomechanical properties among the healing tissues at any time point. The corresponding displacements at force levels recorded in the rabbit PT (21% of normal) [Juncosa et al, 2003] and the goat PT (40% of normal) [Korvick et al, 1996] showed that the healing tissues were too compliant and not functional to 40% levels even after 8 weeks of healing. Error bars indicate SEM. Adapted from Reference 2. Training includes NSF IGERT #0333377.
Credits: David Butler
