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Increasing Efficacy for Lung Cancer Chemotherapeutics: Targeted Drug Delivery via the Protocell

Maximum Intensity Projections

Maximum Intensity Projections

Figure 3: BEAS-2B cell line: No binding on the negative control BEAS-2B cell line when treated with EGF targeted protocell displayed on the left side. No binding on the negative control BEAS-2B cell line when no treatment was added displayed on the right side. The stains seen in the confocal images of the BEAS-2B treated with EGF targeted protocell on the left are as follows: Dapi nuclear stain (contained in the VECTASHIELD HardSet Mounting Medium with DAPI), Invitrogen CellMask Orange plasma membrane stain (C10045), Thermo Scientific Dylight 488 green silica in the protocell. The stains seen in the confocal images of the BEAS-2B no treatment on the right are as follows: Dapi nuclear stain (contained in the VECTASHIELD HardSet Mounting Medium with DAPI) and Invitrogen CellTracker Green CMFDA the cytosol.

Credits: Annikka Jensen, University of New Mexico