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Cell Patch and Membrane Sandwich Electroporation



A nanofluidic “cell patch” device, which integrates layers of polymeric nanochannels into a single microfluidic device, has been developed in the laboratory of IGERT faculty L. James Lee and IGERT trainee Brian Henslee. When an electric field is applied, the nanochannels provide a focused electric field that can accelerate the transport of DNA or drugs into the cells close to the outlet of the nanochannels.

Provide a focused electric field that can accelerate the transport.

Address Goals

Current drug and gene delivery methods have limitations such as safety issues and low efficiency. This affordable “cell patch” device has great potential to deliver genes or drugs efficiently and safely at cell or tissue levels.